Back to Basics: Pancreatitis
Causes of Acute Pancreatitis:
Gallstones - account for at least 35-40% of all cases
Alcohol Use - 2nd most frequent cause
Hypertriglyceridemia - rare (1-4%)
Post ERCP - about 5% of patients are at risk of developing acute pancreatitis within 30 days
Drugs
Autoimmune disese such as SLE or Sjogren Syndrome
Genetic Factors
Abdominal Trauma
Postoperative Complication
Bacterial infections - Legionella, Leptospira, Mycoplasma, Salmonella
Viral infections - mumps, coxsackievirus, CMV, echovirus, hepatitis B
Parasitic infections - Ascaris, Cryptosporidium, Toxoplasma
Hypercalcemia
Hyperparathyroidism
Ischemia
Posterior penetrating ulcer
Scorpion venum
Organophosphate insecticide
Pancreatic or ampullary tumor
Pancreas divisum with ductular narrowing on pancreatogram
Oddi sphincter dysfunction
Idiopathic - 15-20% of cases!
Reference:
Atilla R and Oktay C. Pancreatitis and Cholecystitis. In: Tintinalli JE, Stapczynski J, Ma O, Cline DM, Cydulka RK, Meckler GD. Tintinalli's Emergency Medicine: A Comprehensive Guide. 7th edition. New York, NY: McGraw Hill Companies, Inc.; 2011.