What's the diagnosis? By Dr. Katie Selman
A 30 yo female presents with neck pain and bilateral arm weakness. She states she has been having neck "soreness" for several weeks but for the last 3 days she has had difficulty raising her arms abover her head. On arrival, her temperature is 101.2. MRI was not immediately available so a CT is done and shown below. What's the diagnosis? Scroll down for answer.
Answer: cervical epidural abscess (with associated discitis, osteomyelitis, and spinal cord compression)
- Abscess that develops in the epidural space between the dura and the vertebral body
- S. aureus is most frequent cause
- Pott's disease: spinal epidural abscess due to tuberculosis
- Can occur from hematogenous spread or direct extension from nearby infection
- Most commonly affects thoracic and lumbar spine
- Risk factors
- IV drug use
- immunocompromised state including diabetes and renal disease
- recent spinal instrumentation - up to 22% of epidural abscesses are iatrogenic
- recent spinal trauma
- known distant site of infection
- cancer
- Classic triad - pain, fever, neuro deficit
- most patients will not have all three
- neurological deficit are due to direct compression or ischemia
- Diagnosis
- WBC is not sensitive or specific
- ESR and CRP more sensitive
- MRI for definitive diagnosis
- Pitfall - do not perform lumbar puncture in patient with suspected epidural abscess
- Management
- consult spine surgery
- prolonged IV antibiotic course
Reference
Tanski ME, Ma O. Central Nervous System and Spinal Infections. In: Tintinalli JE, Ma O, Yealy DM, Meckler GD, Stapczynski J, Cline DM, Thomas SH. eds.Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 9eNew York, NY: McGraw-Hill