Neutropenic Enterocolitis aka typhlitis, necrotizing enterocolitis, ileocecal syndrome

Definition:

• intestinal mucosal wall edema and disruption of wall integrity in a neutropenic patient 

Pathogenesis:

• Weakened immune system --> intestinal overgrowth --> invasion of opportunistic bacteria.
• May lead to sepsis and bowel perforation.
• Mortality  22%-50%.

Patient population: